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Meet the mini-organs, take 2


Hello Backers, We would like to thank everyone for your overwhelming supports on our campaign since we started this project. As the projest is progressing, we took sometime to have fun in the lab. Here's our first attempt at catching up with the internet trend these days with TikTok.

This is just a typical day in the lab when we are checking on our little mini-uterus organoids to make sure they are healthy and happy. We grow them in different levels of hormones (estrogen and progesterone) for 28 days to mimick the regular hormone levels during a menstrual cycle in our body. We can use these for disease modeling (like Zika infection) and drug testing later on. How cool is that! #Science

Again, big thanks to everyone for supporting and sharing our story. Cheers, Tee

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  • Morgan Q. Goulding
    Morgan Q. Goulding
    Cool, I want to see them growing! Also, what about trophoblast organoids? Isn't this the kind of cell that the virus has to get through to infect the embryo/fetus?
    Nov 01, 2020
  • Teerawat Wiwatpanit
    Teerawat WiwatpanitResearcher
    Yes Morgan! That's our next step. We will be looking in to the interaction between the endometrial and trophoblast organoids as well as Zika infection and neutralization.
    Nov 01, 2020

About This Project

As of mid-2019, 87 countries have had or still have Zika cases, underlining the importance of this infectious disease. Zika virus can infect the uterus and later infect the infant during pregnancy, causing neurodevelopmental defects at birth. This study will model Zika infection in the lab using uterine mini-organs. We hypothesize that our specific antibodies can neutralize Zika virus in the uterus and thus prevent later transmission from pregnant mother to unborn child.

Blast off!

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