Morgan Q. Goulding

Morgan Q. Goulding

Dec 20, 2020

Group 6 Copy 259
4

Numerous tiny pink blobs

I wasn't expecting to report anything only 48 hours into the trial, but I've seen something maybe never seen before, and I can't keep it to myself. Egg production does seem already to be depressed in the Bt-treated groups (collectively, 0.083 egg masses per snail after 48h, compared to 0.35 in controls), but the surprising thing is a great number (scores) of tiny (1-3mm wide) orangey-pink blobs found stuck to the container walls, all near the water line, in all the Bt-treated groups. None such in the two control containers. The color is the distinctive color of egg masses. Are we seeing the results of numerous abortive egg-laying attempts? That sure would be interesting. I will try to make a time-lapse movie to capture egg-laying (or blob-laying) behavior.

Otherwise, all is well. Snails in all groups are eating their chow, and the water is not going septic over two days. Complete water changes and fresh chow will be done every 48h, with egg mass counts. Next time I will also change the containers, to see if more little blobs appear.

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About This Project

Schistosomiasis is a disease transmitted by snails, responsible for chronic illness of many millions of the world's poorest people, mainly in Africa. This project tests the efficacy of RNAi, a targeted genetic weapon, to kill the snails and thus curtail the spread of the disease. RNAi acts only on specific gene sequences, making it environmentally benign and preventing the evolution of resistance in snail populations. Importantly, this snail-killing material would be very cheap to produce.

Blast off!

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