Can foldscopes, drones, and games help stop a cancer-causing parasite? (pt. II)

Health In Your Hands Diagnostics 501 3 c Non-Profit
Seattle, Washington
BiologyMedicine
$4,000
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About This Project

Let's fight a bloodworm parasite that can lead to bladder cancer in rural Nigeria. Local health workers have been trained to use cheap, foldable microscopes to test and treat people in rural communities. Drone flight surveys find where the snails that carry the parasite live, so we can target them. Monthly fun, game-based lessons in Yoruba teach kids how the disease spreads and how to stay safe. Together, we hypothesize that this approach could reduce illness burden. Will it?

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What is the context of this research?

Schistosomiasis is a parasitic worm infection spread through contact with freshwater containing infected snails, common in rural communities without clean water. The worm silently damages the bladder over years and leads to bladder cancer, yet it rarely gets treated because symptoms like blood in urine are often normalized as "male menstruation" locally.

Ogun State, Nigeria has many affected communities, but the standard diagnostic test requires lab equipment and clinic visits, none of which are realistic for last-mile, rural places here. Treatment (praziquantel) is effective, but it hardly reaches the most rural areas. Meanwhile, treating everyone is futile without addressing the water contact that is reinfecting people.

In August 2026, we visited many communities and found 6 affected communities to help with these interventions: Education, de-centralized and reliable testing and treatment, and environmental control.

What is the significance of this project?

A $2 Foldscope allows for rural microscope use.

Last year, in a project funded by our previous experiment.com campaign, we saw that community health workers can be trained to perform the testing in just a few days, with accuracy of 90% or greater.

But snails and worms don't disappear just because people take medicine, so without environmental solutions, communities can get reinfected time and time again. We are using evidence-based protocols pioneered in Senegal and an iterative, community-led strategy to find solutions that are locally relevant and methodologically sound.

Since kids are often the ones playing and swimming in the water, teaching them why and how the disease spreads can change behavior for the long term in a way pills alone cannot.

This "One Health" approach is the namesake of the project (Schistosomiasis Control from a One Health Perspective), and reflects the breadth of approaches necessary for such a multifaceted issue.

What are the goals of the project?

Diagnosis: Test whether a decentralized "test-and-treat" model, using community health workers and Foldscope microscopes, can catch and treat more infections than waiting for mass drug campaigns alone. We use a stepped-wedge design, so every community eventually gets treated, but we can still measure whether earlier, targeted treatment made a difference.

Ecology: Map where the snails that carry the parasite actually live, using drone imagery of water access points combined with hands-on ground checks, so we can recommend real interventions like clearing trash or invasive plants instead of guessing.

Education: Run monthly, play-based education sessions in Yoruba for school-aged children so they understand how the parasite spreads and can recognize symptoms, aiming to shift behavior around water contact over time and encourage treatment seeking.

Ultimately, we want to know if fighting this parasite is possible at the last mile using a One Health approach.

Budget

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We are a student-led non-profit with an extremely limited budget, which is patched together from institutional medical school grants, reimbursements through global health organizations, and individual donations from Houston fundraising events. Each budget item is carefully thought out to cover bare-minimum operating costs for this project for the near future, as we have regular expenses for the work we are doing.

Fuel, travel, and incidentals cover CHW transport between remote riverine communities and drone site visits at water access points, where car access is no easy feat. "Partner Payment" supports our Nigerian collaborating institution's (Ministry of Health NTD office, FMC Abeokuta, FUNAAB) staff time for community entry, ethics compliance, and coordinating praziquantel distribution. Purchasing and shipping supplies covers urine testing, health lessons, and drone surveys, the core tools enabling rural treatment and snail habitat mapping.

Project Timeline

Timeline Graphic

Phase I (2025, 5 communities, n=418) showed brief training boosted community health worker diagnostic accuracy from 52.5% to 92.1%, now out for publication.

Phase II identified six moderately endemic communities (11-37% disease prevalence) and piloted games, mapped waterways, and sampled eDNA.

Over the next nine months, we'll run a stepped-wedge trial using point-of-care test-and-treat, community education, and environmental mapping across these communities.

Sep 07, 2026

Movement of Praziquantel to Primary Health Centers

Sep 15, 2026

Shipping of environmental eDNA filters in preservative buffer to the U.S.A. for PCR analysis

Sep 21, 2026

First Monthly Educational Visit for Cluster A

Oct 01, 2026

Support Local Team with Renewed Fuel Expense Funds and Supplies

Nov 01, 2026

Finalize Habitat Risk-Mapping from August Fieldwork

Meet the Team

William McCarthy
William McCarthy
Medical Student

Affiliates

UTHealth Houston, MD Anderson
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Caroline Crain
Caroline Crain
Medical Student

Affiliates

McGovern Medical School, UTHealth Houston
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Ifeoluwa George
Ifeoluwa George

Affiliates

FUNAAB
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Richa John
Richa John
Healthcare education designer

Affiliates

McGovern Medical School, Health in Your Hands
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Thomas Copeland
Thomas Copeland
Photographer

Affiliates

Health In Your Hands Diagnostics
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Daniel Amao
Daniel Amao
Cinematographer / Photographer

Affiliates

University Of Jos, Plateau state, Nigeria.
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Siddhant Patil
Siddhant Patil
Medical Student

Affiliates

UTHealth Houston, MD Anderson, Health In Your Hands Diagnostics
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Jon Beaubrun
Jon Beaubrun
Engineer

Support a student-led, international initiative! Our team is composed of creatives, students of medicine, engineering, global health, media, and parasitology. We envision a world where accessible, community-driven diagnostic and health solutions empower individuals and prevent disease through sustainable innovation. We aim to plant seeds of interdisciplinary collaborations, innovative technology, and education to grow scalable, effective, and accessible One Health solutions.

William McCarthy

Hi! I am a lifelong learner, medical student at UTHealth Houston McGovern Medical School, researcher, and writer. I am passionate about environmental health and global health, and channel my curiosity through creative science methods, microscopy, art, and health education efforts. I approach health problems with an open mind, and try to take a widened view of social and ecological forces that shape human illness & healing.

Caroline Crain

Caroline is excited to bring her experience in global health and community-led development to the HIYH team. Her work includes many years with the non-profit AMIGOS, where she worked in rural communities across Latin America to launch community-led sustainable development initiatives as well as five months living in rural Tanzania where she conducted ethnographic research. Now in medical school, she has her sights set on a career in global health genetics where she hopes to empower communities to improve the diagnosis and care of complex genetic conditions. Her approach to global health is grounded in the belief that all communities are capable of solving their most pressing challenges when given the right tools.

Ifeoluwa George

Runs field microscopy and reads samples at the screening table, where the diagnostics meet the community.

Richa John

Medical student, designer, women's health advocate

Thomas Copeland

Thomas Copeland is an adventure and expedition photographer whose work focuses on the intersection of exploration, environmental issues, and global health. He is dedicated to inspiring others and raising awareness through visual storytelling, documenting the individuals who risk their lives in pursuit of exploration, particularly in the fields of medical and scientific research. A wilderness first responder and member of the The Explorers Club, Thomas brings an expedition-minded approach to documenting research, conservation, and exploration in remote environments.


Daniel Amao

Daniel Amao is an energetic, ambitious Person who over the years has extensively developed himself in photography and cinematography through Personal effort and online training.

He has actively been searching for opportunities in areas where he can utilize his knowledge, competently apply his skills and further develop his creative abilities.

Siddhant Patil

Medical student, designer, global health advocate

Jon Beaubrun

Jon is a chemical engineer with experience working in the semiconductor industry as an engineer focused on technology transfer and high volume manufacturing of transistors. Jon also has experience with technology de-risk and scale-up in controlled environment agriculture working on projects ranging from vetting novel sensing technologies to scaling from R&D/pilot to commercial scale production.

Additional Information

Our team spans the people who make this work possible: Dr. Uwem Ekpo, a parasitologist with 20 years on the Oyan River, and Dr. Soneye Islamiat, Ogun State's schistosomiasis control lead, who opened the door to these communities. Regulatory oversight and research ethics are led by Tope Olubodun, a physician at Federal Medical Centre Abeokuta. We're mentored by Manu Prakash, co-inventor of the Foldscope, and disease ecologists at Stanford's Center for Human & Planetary Health. Education sessions are led by Dr. Cynthia Umunnakwe, a parasitologist with years of schistosomiasis education experience in Ogun State, and co-designer of Schisto & Ladders and Hidden Worlds games. Environmental efforts are overseen by Dr. Olubukola Adelakun, a DVM and zoonotic disease researcher who has extensive expertise in the snail hosts of the parasite.

Ethics and safety are of top priority: the study has local ethics approval, all diagnosis (For prevalence assessments) and treatment follow WHO guidelines, participation is voluntary with informed consent, media releases have been signed for all 2026 photographs and video for anyone being represented and during fieldwork we ask permission for study proceedings from every community leader with proper communication with community liaisons known as community mobilizers. Community health workers have been trained by our team in diagnosis, passing an accuracy test prior to study start, and are supervised by Ministry of Health staff throughout to ensure ready access to praziquantel for treating positive cases.


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