Jul 19, 2016
iGEM stands for International Genetically Engineered Machines. It's a synthetic biology research competition and a community that includes graduate students, undergraduates, and even some high schools. For us, it's our life until October when we will present our work at the Giant Jamboree. Here's a good video from HQ about what exactly synthetic biology and iGEM are.
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NU iGEM is creating a delivery system for an innovative antibiotic method centered around CRISPR, a powerful gene editing tool. With CRISPR, researchers can design guide RNA to direct the protein Cas9 to cut out any gene from a cell. In our case, we will target antibiotic resistance genes, leaving pathogens defenseless. We want to harness the natural messenger properties of bacterial outer membrane vesicles (OMVs) to package Cas9 and deliver it to cells as a biological Trojan Horse.
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