eemirhan

I am a molecular medicine researcher focused on ageing biology, neurodegeneration, and the molecular mechanisms underlying diseases such as Parkinson’s disease. My research has taken me across several countries and disciplines, from clinical molecular diagnostics to brain organoids, comparative neurogenesis, and protein-misfolding assays.

I completed my B.Sc. in Molecular Biology and Genetics at Bahçeşehir University and pursued an M.Sc. in Molecular Medicine at Friedrich Schiller University Jena. My research experience has included studying neurogenesis in exceptionally long-lived Greenland sharks and turquoise killifish at Scuola Normale Superiore and CNR in Pisa, working with iPSC-derived brain organoids at Universitätsklinikum Jena, and gaining experience in clinical molecular and genetic diagnostics.

My current research at the University of Oxford’s Nuffield Department of Clinical Neurosciences focuses on developing α-synuclein seed amplification assays for Parkinson’s disease research. I use approaches including RT-QuIC, TEM and ELISA to investigate and validate protein seeding and aggregation.

Working directly with RT-QuIC made me interested in another problem: these experiments generate rich kinetic information about how proteins aggregate, but much of that information may be lost when results are reduced to conventional summary measurements.

This led me to independently develop Quicore, a cloud-based R Shiny platform for automated analysis and visualisation of RT-QuIC experiments.

My next goal is to investigate whether machine learning can identify disease-specific signatures hidden within protein aggregation kinetics. In the longer term, I hope to develop an “Aggregatome Atlas” that maps these signatures across neurodegenerative diseases and helps researchers investigate how protein-misfolding diseases differ, overlap, and progress.

September 2026