The cause of onset of autoimmune disease is poorly understood, but may be linked to exposure to certain chemicals. We plan to study the response of melanocytes to monobenzone and thyrocytes' response to PBDE and BPA to determine how they lead to autoimmune diseases like vitiligo and Hashimoto's thyroiditis. To do this, we will look at the antigens (molecules presented to immune cells) on the cells' surfaces using mass spectrometry.