Claire Komives

Claire Komives

May 17, 2015

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Cocktail of antivenoms

This week we will test a cocktail of antivenom compounds with the Russell Viper venom in mice. This could be a big breakthrough if we are able to use low cost chemicals to treat the envenomation of this deadly snake.

This snake is a Russell Viper. It has venom with both hemorrhagic and neurotoxic compounds in it. We will see if we can make a protective mixture of compounds to prevent death from envenomation by this snake. The funds you have provided will give me the chance to determine if we can save lives with our strategy.

Thanks for your support! I hope to complete the set of proposed experiments by the end of this summer. I hope to keep you posted!

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About This Project

Death by snake venom in India, Africa, and South America are substantial. Traditional antidotes are prohibitively expensive ($100/dose) and have side effects. A new peptide-based antidote shows promise in treating certain snake venoms with no side effects. However, this needs further testing in Indian snakes, and needs to be cheaper. With your help, we can test this antidote in four prevalent Indian snakes, and begin designing a low cost bioprocess – targeting a $1/dose treatment.

Blast off!

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