Patrick Frost, PhD

Patrick Frost, PhD

Feb 10, 2016

Group 6 Copy 95
3

A special honor

This afternoon, we got this nice note from the editors of Molecular Cancer Research. It is always nice to get published but this is the first time that one of our studies was a special feature in the journal. "Dear Dr. Frost:

Congratulations on the acceptance of your above-referenced manuscript, which is scheduled to be published in the March issue of Molecular Cancer Research.

We are pleased to inform you that the Editors have selected your article to be featured in a section of the journal called 'MOLECULAR CANCER RESEARCH Highlights: Selected Articles from This Issue.'"

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About This Project

BBRI and Los Angeles VA Medical Center

Multiple myeloma (MM) is a cancer of the bone marrow made up of plasma cells (a type of antibody-producing white blood cells). Low oxygen levels (called hypoxia) in the bone marrow increases gene expression in MM tumor cells as part of an adaptive survival response. We are targeting this hypoxic response with an experimental drug that blocks expression of these genes to ask if this molecule kills MM in the bone marrow. This is a novel approach to treat MM, an incurable disease.

Blast off!

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