Our project aims to provide a method of detecting pancreatic cancer in humans. We are using yeast in this project as a method for expressing Cripto-1, a membrane protein which binds to a biomarker for pancreatic cancer. We hope to be able to couple CR-1 binding to a reporter inside yeast for indication of the presence of the biomarker in human blood serum. This could offer insight into the potential for synthetic biology as an important medical tool in the future.