Venomous caterpillars of the genus Lonomia cause deadly accidents in Colombia. In Brazil it is estimated that 30% of individuals who come into contact with these caterpillars die in the absence of treatment. The most widely used treatment is the Antilonomia serum, produced by the Butantan Institute in Brazil. However, in our experiments, it has been found to be less effective against colombian species. We aim to develop a synthetic antivenom against Lonomia using a cell-free system.