Primary cortical neurons and neural stem cells in culture
The Zika virus will infected two types of cells:
-Neural stem cells (NSCs) which are forming neurospheres in cultures
-Primary cortical neurons (PCN) obtained from mice fetus brains
About This Project
Zika virus is a rapidly emerging virus that is spreading throughout the Western Hemisphere. It is predicted to spread throughout the Americas by the end of 2016. Previously thought to be a mild disease, Zika virus is now associated with a significant increase in microcephaly. In order to learn about how Zika virus interacts with cells in the brain, we will infect progenitor and mature neural cells with Zika virus and determine if the virus can replicate and impact survival and proliferation.
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