Group 6 Copy 112
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Back to the drawing board.

It's a deceivingly simple question--one that has consumed geneticists' minds for nearly four decades now (circa 1970). How to edit any gene. Last year, someone found the answer.

Feng Zhang claimed the "biggest biotech discovery of the century" when he created CRISPR/Cas9 technology for highly-specific, in vivo gene editing. Don't be surprised when he wins a Nobel Prize.

Zhang focused on this completely novel, niche solution while most of science--including myself--looked at popular research on engineered nucleases including ZFNs and TALENs. Over the last year, CRISPRs made huge strides, moving rapidly from editing human cells in lab to reversing diseases in living organisms. Meanwhile, I finally got approved to have keyless access to my new lab.

So now, I'm working on rewording the question I initially asked. We now know how to edit any gene. Now, what do we do with that? Answer coming at you guys in a couple weeks.

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  • Oscar Jasklowski
    Oscar JasklowskiBacker
    Thanks for the update, Vip! It sounds like you're switching over to CRISPR/Cas9 technology then?
    Mar 10, 2015
  • Viputheshwar Sitaraman
    Viputheshwar SitaramanResearcher
    Yup! Right now I'm thinking of using it for unconventional purposes outside biomedical research with industrial applications (ie. tattoos).
    Mar 10, 2015
  • Oscar Jasklowski
    Oscar JasklowskiBacker
    Awesome! Why do tattoos need CRISPR tech?
    Mar 10, 2015

About This Project

Imagine being able to edit any gene—from Alzheimer's and cancer to eye color and balding. Today, that is almost possible, with gene scissors: we simply cut out the original gene, then paste the new one.
The Problem: We can cut genes, but only hope they get pasted.
The Solution: Gene glue for gene scissors.
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A biology project funded by 13 people

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