Drug-resistant tuberculosis (TB) is a race against time. Culture-based methods can take almost 8 weeks to reveal drug resistance. What if we could get answers sooner? ActiWGS TB asks: Can we recover enough DNA from blood spiked with Bacillus Calmette-Guérin (BCG), a safer TB model, for reliable whole-genome sequencing (reading bacterial DNA) without culture? We believe we can. We'll measure completeness and reliability, working toward 72-hour resistance results to ensure better patient outcomes.