In Sikkim, an Eastern Himalayan state, there is tremendous scarcity of potable drinking water, and people are solely dependent on spring water. From our preliminary study, it was found that most of the water sources are contaminated with antibiotic resistance pathogens including MDR strains. So, in this project we want to study the distribution of "Antibiotic Resistance Genes (ARGs)" in different potable water sources of Sikkim.